abstract：PURPOSE:In this longitudinal study we explored the relationships between plasma n-3 and n-6 polyunsaturated fatty acids (PUFAs) and Δ5 and Δ6 desaturase activities (D5D and D6D, respectively) and fasting lipids in youth with type 1 diabetes (T1D). METHODS:Incident cases of T1D in youth <20years of age who were seen fo...

journal_title：Journal of diabetes and its complications

authors： Couch SC,Crandell J,King I,Peairs A,Shah AS,Dolan LM,Tooze J,Crume T,Mayer-Davis E

更新日期：2017-01-01 00:00:00

abstract：AIMS:To investigate the renal pathological implications in type 2 diabetes mellitus patients with renal involvement. METHODS:A total of 328 type 2 diabetes mellitus (T2DM) patients with renal involvement who underwent a renal biopsy and received follow-up for at least one year were recruited in our study. The patients...

journal_title：Journal of diabetes and its complications

authors： Li L,Zhang X,Li Z,Zhang R,Guo R,Yin Q,Yang L,Yue R,Su B,Huang S,Xu H,He C,Liu F

更新日期：2017-01-01 00:00:00

abstract：AIM/HYPOTHESIS:Cluster determinant 36 (CD36), a fatty acid transporter, was reported to have a pivotal role in glucotoxicity-induced beta cell dysfunction. However, little is known about how glucotoxicity influences CD36 expression, and it is unknown whether this action can be counteracted by metformin. In the present ...

journal_title：Journal of diabetes and its complications

authors： Moon JS,Karunakaran U,Elumalai S,Lee IK,Lee HW,Kim YW,Won KC

更新日期：2017-01-01 00:00:00

abstract：AIMS:Discrimination is linked to negative health outcomes, but little research has investigated how the cumulative effect of discrimination impacts perceptions of care. This study investigated the influence of cumulative perceived discrimination on quality of care, patient-centeredness, and dissatisfaction with care in...

journal_title：Journal of diabetes and its complications

authors： Cykert DM,Williams JS,Walker RJ,Davis KS,Egede LE

更新日期：2017-01-01 00:00:00

abstract：AIMS:To compare the effects of structured and routine testing regimens used in self-monitoring of blood glucose (SMBG) on glycemic control and diabetes self-management in insulin-naïve type 2 diabetes patients. METHODS:Sixty-two outpatients with insulin-naïve type 2 diabetes were randomly allocated into two less-frequ...

journal_title：Journal of diabetes and its complications

authors： Nishimura A,Harashima SI,Fujita Y,Tanaka D,Wang Y,Liu Y,Inagaki N

更新日期：2017-01-01 00:00:00

abstract：AIM:To identify the prevalence and effect of hepatopathies of different etiologies among pediatric patients with type 1 diabetes mellitus (T1DM) using transient elastography (TE) and its relation to glycemic control. METHODS:One hundred T1DM patients were studied focusing on liver functions, fasting lipid profile, hem...

journal_title：Journal of diabetes and its complications

authors： Elkabbany ZA,Elbarbary NS,Ismail EA,Mohamed NA,Ragab D,Abdel Alem S,Ezzat YM,Maurice SS,Hashem NU

更新日期：2017-01-01 00:00:00

abstract：OBJECTIVES:Increased Toll like receptors (TLRs) especially 2 and 4 have been demonstrated in obesity, metabolic syndrome (MetS) and diabetes resulting in increased cellular inflammation. Since we have shown increased TLR2 and 4 activities in both T1DM and T2DM and MetS, we wanted to elucidate the mechanisms of this ste...

journal_title：Journal of diabetes and its complications

authors： Pahwa R,Jialal I

更新日期：2016-08-01 00:00:00

abstract：AIM:To analyze the impact of glucose-lowering drugs on metastases in women living in Germany who have been diagnosed with breast cancer (BC) and type 2 diabetes mellitus (T2DM). METHODS:Women initially diagnosed with BC (2004-2013) were identified in the IMS Disease Analyzer database. Patients with a documentation of ...

journal_title：Journal of diabetes and its complications

authors： Jacob L,Kostev K,Rathmann W,Kalder M

更新日期：2016-08-01 00:00:00

abstract：AIM:To evaluate the use of the FINDRISC score in an overweight and obese population to predict glucose status. METHODS:In 651 overweight/obese subjects (M/F: 193/458, age 43±13 y, BMI 38.2±6.1kg/m(2)) glucose status was tested using OGTT and HbA1c. Furthermore, the FINDRISC questionnaire and CT visceral fat (VAT) and ...

journal_title：Journal of diabetes and its complications

authors： Meijnikman AS,De Block CE,Verrijken A,Mertens I,Corthouts B,Van Gaal LF

更新日期：2016-08-01 00:00:00

abstract：AIMS:To quantify the risk of hospitalization for infections in Indigenous Australian adults with diabetes in rural and remote communities. METHODS:2787 Indigenous adults including 396 with diabetes at baseline from 19 communities in North Queensland from 1998 to 2007 were included in the study. Main measures were weig...

journal_title：Journal of diabetes and its complications

authors： Li M,McDermott R

更新日期：2016-08-01 00:00:00

abstract：AIMS:Investigate the importance of treating diabetes by evaluating mortality risk of untreated and medically-treated diabetic patients. METHODS:Historical prospectively collected observational data of hospitalized patient ≥18years, admitted for any-cause to medical wards, between January 2011 and December 2013. Main o...

journal_title：Journal of diabetes and its complications

authors： Akirov A,Dicker D,Shochat T,Shimon I

更新日期：2016-08-01 00:00:00

abstract：AIM:To assess the contribution of β-cell dysfunction and insulin resistance to type 2 diabetes (T2D) in obese and non-obese Chinese people. METHODS:In this cross-sectional study, we recruited 1384 newly diagnosed T2D patients and 1712 healthy controls. Insulin resistance was estimated by homeostasis model assessment o...

journal_title：Journal of diabetes and its complications

authors： Liu J,Wang Y,Hu Y,Leng S,Wang G

更新日期：2016-07-01 00:00:00

abstract：AIMS:The aim of this study was to examine the associations between possible indices of obesity based on information on weight history and the incidence of microvascular complications. METHODS:A cohort of individuals with type 2 diabetes from 59 institutes in Japan was followed for 8years. Patients were classified into...

journal_title：Journal of diabetes and its complications

authors： Tanaka S,Tanaka S,Iimuro S,Ishibashi S,Yamashita H,Moriya T,Katayama S,Akanuma Y,Ohashi Y,Yamada N,Araki A,Ito H,Sone H,Japan Diabetes Complications Study Group.

更新日期：2016-07-01 00:00:00

abstract：OBJECTIVES:Hyperglycemia-induced inflammation is central to the vascular complications in diabetes. Toll-like receptors (TLRs) are key players in regulating inflammatory responses. There are sparse data on the role of TLR2 and TLR4 in regulating human macrovascular aortic endothelial cells (HMAECs) inflammation and gly...

journal_title：Journal of diabetes and its complications

authors： Pahwa R,Nallasamy P,Jialal I

更新日期：2016-05-01 00:00:00

abstract：OBJECTIVE:The aim of this study is to investigate the relationship between plasma NH2-terminal pro-brain natriuretic peptide (NT-proBNP) levels and diabetic nephropathy in type 2 diabetic patients. METHODS:The records of 983 patients with type 2 diabetes hospitalized in the Endocrinology and Metabolism Department of P...

journal_title：Journal of diabetes and its complications

authors： Zhou L,Cai X,Li M,Han X,Ji L

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND:Vascular complications are the leading cause of morbidity and mortality among patients with type 1 and type 2 diabetes mellitus. These vascular abnormalities result of a chronic hyperglycemic state, which leads to an increase in oxidative stress and inflammatory responses. AIM:This review addresses the rela...

journal_title：Journal of diabetes and its complications

authors： Domingueti CP,Dusse LM,Carvalho Md,de Sousa LP,Gomes KB,Fernandes AP

更新日期：2016-05-01 00:00:00

abstract：:Latinos are at increased risk for obesity and type 2 diabetes (T2D). Well-designed information technology (IT) interventions have been shown to be generally efficacious in improving diabetes self-management. However, there are very few published IT intervention studies focused on Latinos. With the documented close of ...

journal_title：Journal of diabetes and its complications

authors： López L,Tan-McGrory A,Horner G,Betancourt JR

更新日期：2016-04-01 00:00:00

abstract：AIMS:The cardiovascular risk factors and diabetic complications are related to coronary atherosclerosis. However, the evaluation of the prevalence of coronary atherosclerosis based on their accumulation remains to be determined. METHODS:247 consecutive Chinese subjects with type 2 diabetes but without history of coron...

journal_title：Journal of diabetes and its complications

authors： Rong J,Bai SR,Chen YL,He C

更新日期：2016-04-01 00:00:00

abstract：:Cardiovascular diseases are the major cause of mortality in diabetes patients. Increased levels of glycated low density lipoprotein (glyLDL) are detected in diabetic patients. Endothelial nitric oxide synthase (eNOS) generates nitric oxide, which is responsible to endothelium-dependent vasodilation. The impact of glyL...

journal_title：Journal of diabetes and its complications

authors： Mohanan Nair M,Zhao R,Xie X,Shen GX

更新日期：2016-04-01 00:00:00

abstract：AIMS:To estimate prevalence and incidence of auto-immune thyroid disease and thyroid auto-antibodies in an unselected cohort of patients with DM1, including stratification by age, gender and duration of diabetes. METHODS:Patients with T1D visiting our outpatient clinic between 1995 and 2011 were included. We calculate...

journal_title：Journal of diabetes and its complications

authors： Nederstigt C,Corssmit EP,de Koning EJ,Dekkers OM

更新日期：2016-04-01 00:00:00

abstract：AIMS:The present study aimed to examine the nonlinear associations between risk factors and mild hypoglycemia in Chinese patients with type 2 diabetes mellitus (T2DM). METHODS:From May 2013 to August 2013, we conducted a cross sectional survey of 6633 inpatients with T2DM and without severe hypoglycemia, aged 21-77 ye...

journal_title：Journal of diabetes and its complications

authors： Gu W,Ren Y,Ji L,Hong T,Mu Y,Guo L,Li Q,Tian Q,Yang X

更新日期：2016-04-01 00:00:00

abstract：AIMS:The Haptoglobin (HP) 2-2 genotype increases cardiovascular diabetes complication incidence. In type 1 diabetes, HP 2-2 also predicts declining kidney function and end-stage renal disease. We investigated whether HP 2-2 predisposes to cardio-renal mortality, while considering other causes of death as competing risk...

journal_title：Journal of diabetes and its complications

authors： Costacou T,Orchard TJ

更新日期：2016-03-01 00:00:00

abstract：AIMS:We aimed to analyze the impact of baseline factors on the efficacy of α-lipoic acid (ALA) over 4 years in the NATHAN 1 trial. METHODS:This was a post-hoc analysis of the NATHAN 1 trial, a 4-year randomized study including 460 diabetic patients with mild-to-moderate polyneuropathy using ALA 600 mg qd or placebo. A...

journal_title：Journal of diabetes and its complications

authors： Ziegler D,Low PA,Freeman R,Tritschler H,Vinik AI

更新日期：2016-03-01 00:00:00

abstract：:The relationships between hypoglycemia, frailty and dementia appear to be reciprocal and can lead to a vicious circle. Frailty appears to be a crucial factor increasing the risk for both hypoglycemia and dementia, initiating the reciprocal relationships. Weight loss is likely to be the underlying risk factor for frail...

journal_title：Journal of diabetes and its complications

authors： Abdelhafiz AH,McNicholas E,Sinclair AJ

更新日期：2016-01-01 00:00:00

abstract：AIM:To examine the relationship between immigration and dietary patterns among South Asian adults at risk for diabetes and living in Canada. METHODS:We recruited 428 South Asian adults affiliated with Sikh and Hindu temples in Metro Vancouver. Of the total sample, 422 completed self-report surveys including demographi...

journal_title：Journal of diabetes and its complications

authors： Kandola K,Sandhu S,Tang T

更新日期：2016-01-01 00:00:00

abstract：AIMS:To investigate the discontinuation of oral antihyperglycemic agents (OHA), and examine factors associated with OHA discontinuation, and the effect of OHA discontinuation on glycemic control and healthcare utilization among diabetes patients prescribed dual OHA therapy. METHODS:We identified 23,612 adult patients ...

journal_title：Journal of diabetes and its complications

authors： Reynolds K,An J,Wu J,Harrison TN,Wei R,Stuart B,Martin JP,Wlodarczyk CS,Rajpathak SN

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Rotator cuff tears are the most common cause of shoulder disability in people older than 50years, and surgical intervention is usually required for restoring functioning. However, in patients undergoing rotator cuff repair surgery, patients with DM had poorer functional outcomes than those without DM, and he...

journal_title：Journal of diabetes and its complications

authors： Huang SW,Wang WT,Chou LC,Liou TH,Chen YW,Lin HW

更新日期：2016-01-01 00:00:00

abstract：INTRODUCTION:Prevalence of partial remission ranges between 20% and 80% in the initial course of type 1 diabetes. In this phase of the disease, a substantial insulin secretion contributes to good metabolic control. The aim of the study was to determine the association between presence of partial remission and occurrenc...

journal_title：Journal of diabetes and its complications

authors： Niedzwiecki P,Pilacinski S,Uruska A,Adamska A,Naskret D,Zozulinska-Ziolkiewicz D

更新日期：2015-11-01 00:00:00

abstract：AIMS:The renin-angiotensin-aldosterone system (RAAS), bone morphogenetic protein (BMP) and WNT pathways are dysregulated in diabetic kidney disease (DKD). Urine excretion of angiotensinogen, gremlin-1 and matrix metalloproteinase-7 (MMP-7), components of the RAAS, BMP and WNT pathways, respectively, is increased in DKD...

journal_title：Journal of diabetes and its complications

authors： Afkarian M,Zelnick LR,Ruzinski J,Kestenbaum B,Himmelfarb J,de Boer IH,Mehrotra R

更新日期：2015-11-01 00:00:00

abstract：INTRODUCTION:One of the diagnostic tools of neuropathetic pain (NP) relies on screening questionnaires including the Leeds Assessment of Neuropathic Symptoms and Signs (LANSS) questionnaire. AIM:To apply and validate the LANSS questionnaire in Greek population. To assess any correlation between LANSS score and visual ...

journal_title：Journal of diabetes and its complications

authors： Spanos K,Lachanas VA,Chan P,Bargiota A,Giannoukas AD

更新日期：2015-11-01 00:00:00

abstract：AIMS:The GLP-1 receptor agonist liraglutide improves impaired pancreatic β-cell function, thereby exerting glucose-lowering effects. However, the association of remaining β-cell function with long-term therapeutic efficacy of liraglutide remains largely unknown. METHODS:Patients with type 2 diabetes who started liragl...

journal_title：Journal of diabetes and its complications

authors： Usui R,Yabe D,Kuwata H,Murotani K,Kurose T,Seino Y

更新日期：2015-11-01 00:00:00

abstract：AIMS:Type 2 diabetes (T2DM) is associated with cognitive impairment. We examined whether undiagnosed cognitive impairment in T2DM-patients is associated with a reduced health status and depressive symptoms. METHODS:In an observational study, 225 T2DM-patients aged ≥70years were examined at their homes and (some of the...

journal_title：Journal of diabetes and its complications

authors： Koekkoek PS,Biessels GJ,Kooistra M,Janssen J,Kappelle LJ,Rutten GE,Cog-ID study group.

更新日期：2015-11-01 00:00:00

abstract：AIM:Posttransplantation diabetes mellitus (PTDM) is a common complication after renal transplantation leading to increased cardiovascular morbidity and mortality. In subjects with type 2 diabetes (T2DM) increased glycemic variability and poor glycemic control have been associated with cardiovascular complications. We t...

journal_title：Journal of diabetes and its complications

authors： Werzowa J,Pacini G,Hecking M,Fidler C,Haidinger M,Brath H,Thomas A,Säemann MD,Tura A

更新日期：2015-11-01 00:00:00

abstract：AIM:To evaluate the effects on glycemic excursions during bicarbonate dialysis (BHD) compared to hemodiafiltration (HDF) in type 2 diabetic or not diabetic patients affected by end-stage renal disease (ESRD). MATERIAL AND METHODS:Thirty-six patients (20 affected by type 2 diabetes mellitus, and 16 not diabetic patient...

journal_title：Journal of diabetes and its complications

authors： Derosa G,Libetta C,Esposito P,Borettaz I,Tinelli C,D'Angelo A,Maffioli P

更新日期：2015-11-01 00:00:00

abstract：BACKGROUND:Apolipoprotein A-II (ApoA-II) constitutes approximately 20% of the total HDL protein content. The results of various studies on the relationship between cardiovascular diseases (CVD) and the plasma ApoA-II level are contradictory. The aim of this study was to determine the relationship between ApoA-II polymo...

journal_title：Journal of diabetes and its complications

authors： Koohdani F,Sadrzadeh-Yeganeh H,Djalali M,Eshraghian M,Keramat L,Mansournia MA,Zamani E

更新日期：2015-09-01 00:00:00

abstract：OBJECTIVE:Unprovoked "A-β+" Ketosis-Prone Diabetes (KPD), a unique diabetic syndrome of adult-onset, obesity and proneness to ketoacidosis, is associated with rapid recovery of β cell function and insulin-independence. Whereas most patients experience prolonged remission, a subset relapses early to insulin dependence. ...

journal_title：Journal of diabetes and its complications

authors： Gaba R,Gambhire D,Uy N,Gonzalez EV,Iyer D,Hampe CS,Ram N,Balasubramanyam A

更新日期：2015-09-01 00:00:00

abstract：:Distal symmetric peripheral polyneuropathy (DSPN) is a highly prevalent complication of diabetes. However, underlying pathophysiological mechanisms are multiple and not well understood. The aim of our study was to analyze the oxidative stress levels in circulating mononuclear cells by measuring the glutathione system,...

journal_title：Journal of diabetes and its complications

authors： Mendez MM,Folgado J,Tormo C,Artero A,Ascaso M,Martinez-Hervás S,Chaves FJ,Ascaso JF,Real JT

更新日期：2015-09-01 00:00:00

abstract：OBJECTIVE:Matrix metalloproteinases (MMPs) play an important role in pathogenesis of atherosclerosis and vascular disease. We hypothesized that MMP-2 might be a susceptibility gene for cardiovascular disease (CVD) in diabetes. The aim of this study was to evaluate the association between C(-1306)T functional polymorphi...

journal_title：Journal of diabetes and its complications

authors： Buraczynska M,Dragan M,Buraczynska K,Orlowska-Kowalik G,Ksiazek A

更新日期：2015-08-01 00:00:00

abstract：AIMS:To highlight the differences between eight international expert panel diagnostic criteria (either current or outdated but in use) for the diagnosis of gestational diabetes mellitus (GDM) and implications of switching to the International Association of Diabetes in Pregnancy Study Groups (IADPSG) criterion. METHOD...

journal_title：Journal of diabetes and its complications

authors： Agarwal MM,Dhatt GS,Othman Y

更新日期：2015-05-01 00:00:00

abstract：AIMS:Several central nervous disorders are associated with metabolic syndrome (MetS) and type 2 diabetes. Reduction in brain-derived neurotrophic factor (BDNF) is involved in the mechanism of central nervous dysfunction. BDNF is up-regulated after exercise, but it is not known whether increased BDNF is related to incre...

journal_title：Journal of diabetes and its complications

authors： Tsai SW,Chan YC,Liang F,Hsu CY,Lee IT

更新日期：2015-04-01 00:00:00